Document Type
Thesis
Date of Award
5-31-1983
Degree Name
Master of Science in Biomedical Engineering - (M.S.)
Department
Biomedical Engineering Committee
First Advisor
Stanley S. Reisman
Second Advisor
Joseph Frank
Third Advisor
Joseph J. Strano
Abstract
In order to more adequately simulate the human pituitary-ovarian cycle further refinements were made to the original Bogumil and Feng computer models. This involved the inclusion of equations which mathematically describe the peripheral conversion of prehormones and a subroutine showing the effect of plasma proteins, TeBG, CBG, and albumin on the total concentration of estradiol, progesterone, testosterone, androstenedione, dehydroepiandrosterone and estrone.
Once the models were functioning properly, values for the normal state and for the disease condition, Polycystic Ovary Syndrome (PCO), were obtained. In most cases there exists good agreement between the results reported in the literature and those generated by the models.
Recommended Citation
Blencowe, Robert Charles, "Computer simulation of the human hypophysial-ovarian system" (1983). Theses. 3502.
https://digitalcommons.njit.edu/theses/3502
