Document Type

Thesis

Date of Award

12-31-2019

Degree Name

Master of Science in Biology - (M.S.)

Department

Federated Department of Biological Sciences

First Advisor

Eric Scott Fortune

Second Advisor

Horacio G. Rotstein

Third Advisor

Kristen E. Severi

Abstract

Predicting seasonal variation in influenza epidemics is an ongoing challenge. To better predict seasonal influenza and provide early warning of pandemics, a novel approach to Influenza-Like-Illness (ILI) prediction was developed. This approach combined a deep neural network with ILI, climate, and population data. A predictive model was created using a deep neural network based on TensorFlow 2.0 Beta. The model used Long-Short Term Memory (LSTM) nodes. Data was collected from the Center for Disease Control, the National Center for Environmental Information (NCEI) and the United States Census Bureau. These parameters were temperature, precipitation, wind speed, population size, vaccination rate and vaccination efficacy. Temperature was confirmed as the greatest predictor for ILI rates, with precipitation providing a small increase in predictive power. After training, the model was able to predict ILI rates 10 weeks out. As a result of this thesis, a framework was developed that may be applied to weekly ILI tracking as well as early prediction of outlier pandemic years.

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.