Novel delivery systems by melt compounding polymers with drug fucntionalzed nanoclays

Document Type

Conference Proceeding

Publication Date

9-27-2010

Abstract

In this study, anionic nanoclays are fiinctionalized with active pharmaceutical ingredients (APIs) which intercalate into the interspacing of the clays through ion exchange reactions and then melt mixed with appropriate polymer matrices. The intercalated API is further released upon demand by physiochemical changes in an appropriate environment. The aspects of drug release from different systems containing dispersed or dissolved APIs in polymeric matrices are compared with those of systems containing nanoclays fiinctionalized with different APIs in attempts to develop novel drug delivery systems.

Identifier

77956920764 (Scopus)

ISBN

[9781617386602]

Publication Title

Annual Technical Conference ANTEC Conference Proceedings

First Page

1650

Last Page

1654

Volume

3

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