Semicontinuous pH Parametric Pumping: Process Characteristics and Protein Separations

Document Type

Article

Publication Date

2-1-1981

Abstract

A semicontinuous pH parametric pump was experimentally and theoretically investigated using the model system of hemoglobin-albumin-CM Sepharose. A mathematical model with finite mass transfer was developed, and agrees quite well with experimental data. Various factors affecting separations were exam-ined. It is shown that under certain operating conditions, the continuous process can be operated with large feed throughput and with high separation factors. Copyright © 1981 by Marcel Dekker, Inc.

Identifier

0019679221 (Scopus)

Publication Title

Separation Science and Technology

External Full Text Location

https://doi.org/10.1080/01496398108070224

e-ISSN

15205754

ISSN

01496395

First Page

43

Last Page

61

Issue

1

Volume

16

Grant

ENG 77-04129

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