Design and characterization of a controlled wet spinning device for collagen fiber fabrication for neural tissue engineering
Document Type
Conference Proceeding
Publication Date
6-16-2011
Abstract
Type I collagen was extruded into well-defined fibers using a novel controlled wet spinning device. The device significantly improved the yield of collagen fibers on the micron scale. Collagen scaffold materials fabricated from the device will provide contact-guided growth of neuronal cultures. Fibers composed of different weight percentages, 75, 2, and 3.4 wt% collagen dispersions, were used to validate Schwann cell alignment along the fibers. Interestingly, the different concentrations of extruded collagen dispersions demonstrated unique morphologies and directed growth patterns of Schwann cells. © 2011 IEEE.
Identifier
79958693796 (Scopus)
ISBN
[9781612848273]
Publication Title
2011 IEEE 37th Annual Northeast Bioengineering Conference Nebec 2011
External Full Text Location
https://doi.org/10.1109/NEBC.2011.5778585
Recommended Citation
DeRosa, K. E.; Siriwardane, M. L.; and Pfister, B. J., "Design and characterization of a controlled wet spinning device for collagen fiber fabrication for neural tissue engineering" (2011). Faculty Publications. 11311.
https://digitalcommons.njit.edu/fac_pubs/11311
