Date of Award

Spring 1999

Document Type

Thesis

Degree Name

Master of Science in Electrical Engineering - (M.S.)

Department

Electrical and Computer Engineering

First Advisor

Andrew Ulrich Meyer

Second Advisor

Edward Joseph Haupt

Third Advisor

Timothy Nam Chang

Fourth Advisor

Stanley S. Reisman

Abstract

The oscillatory potential (OP), a signal component of the electroretinogram (ERG), was investigated to determine correlation of the OP and pathological conditions of the inner retina. Large transients characterize the ERG. Such transients stimulate a filter's natural response. Since these responses can co-occur with the OP, a distorted OP will be extracted. A proposed signal windowing and padding technique for conditioning the ERG signal has been implemented for the extraction of a ntnimally distorted OP.

Windowing is used to capture only the OP period. The windowed ERG signal is then signal conditioned to generate initial values for the filter's state variables. Such correct initial conditions eliminate the perturbations created from filtering the windowed ERG. OPs were successfully extracted from a database of fifty human ERGs. The extracted OPs did not display any filter-induced oscillations and did provide some indication of the retina's pathology.

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