Document Type


Date of Award

Spring 5-31-1975

Degree Name

Master of Science in Chemical Engineering - (M.S.)


Chemical Engineering and Chemistry

First Advisor

Richard Clyde Parker

Second Advisor

David S. Kristol

Third Advisor

Angelo J. Perna


The kinetics of the reaction of iodoacetamide with lysine, polylysine, N-α-Acetyl lysine, and N-ε-Acetyl lysine, have been studied. The investigation was done at 23° C ± 123° C, as a function of pH, and concentration. In all cases it was noted that the rate of reaction increased as the pH increased. The rate data was analyzed in order to obtain the second order rate constants. In addition, the effects of the reactive site's environment on the rate was demonstrated.