Synthesis and characterization of isosorbide derived polyols as highly effective humectants

Document Type

Conference Proceeding

Publication Date

6-8-2010

Abstract

Isosorbide is a bicyclic ether derivative of glucose. It is recognized as a "green" substance and is hygroscopic at > 30% relative humidity. Since it is water soluble and harmless, isosorbide is used as a multi-functional carrier in many pharmaceutical and cosmetic applications. In order to find a "green" replacement for polyethyleneoxide in cosmetic formulations, glycerine (propanetriol) a known skin softener and humectant was chemically combined with isosorbide to improve the hygroscopic properties. The synthetic route developed for this work not only provides a series of highly effective humectants but also generates a range of epoxides which are promising candidates for replacing bisphenol-A based epoxies and also as plastic additives. All the intermediates generated during the syntheses were characterized by NMR and FTIR. Water absorption tests were conducted in a humidity chamber with specific relative humidities. ©2010 IEEE.

Identifier

77953032750 (Scopus)

ISBN

[9781424468799]

Publication Title

Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference Nebec 2010

External Full Text Location

https://doi.org/10.1109/NEBC.2010.5458231

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