Spatial coordinate corrected motion tracking for optical coherence elastography

Document Type

Conference Proceeding

Publication Date

1-1-2020

Abstract

We develop a spatial coordinate corrected (SCC) motion tracking method for optical coherence elastography. SCC motion tracking refers the instantaneous velocity field extracted from optical coherence tomography (OCT) data to the laboratory coordinate system and accurately reconstructs the displacement field established during the mechanical excitation (compression) process. We acquired image data from compression OCE experiments on human breast tissue specimens, and reconstructed the displacement field through Doppler analysis of OCT data. Our results suggested that SCC tracking enables accurate reconstruction of displacement field, and enables effective identification mechanical heterogeneity that can be used as a biomarker for cancer diagnosis and tumor margin assessment.

Identifier

85082516214 (Scopus)

ISBN

[9781510632479]

Publication Title

Progress in Biomedical Optics and Imaging Proceedings of SPIE

External Full Text Location

https://doi.org/10.1117/12.2546070

ISSN

16057422

Volume

11242

Grant

1R15CA213092-01A1

Fund Ref

National Institutes of Health

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