Review on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for the rapid screening of microbial species: A promising bioanalytical tool
Document Type
Article
Publication Date
12-1-2020
Abstract
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has achieved considerable progress in bacterial analysis, allowing the identification of pathogenic microbial species at both species and genus level. This review analyzes the recent progress and implications of MALDI-TOF MS as a promising biotool for the rapid analysis of multiple pathogenic microbes in environmental and clinical samples. Nanoparticle (NP)-based MALDI-TOF MS methods for accurate bacterial analysis are also discussed. This review also summarizes sample preparation protocols and used matrix solutions in MALDI-TOF MS for the analysis of microbial species. Furthermore, we discuss the currently established advantages and limitations of MALDI-TOF MS in identifying microbial species.
Identifier
85089342645 (Scopus)
Publication Title
Microchemical Journal
External Full Text Location
https://doi.org/10.1016/j.microc.2020.105387
ISSN
0026265X
Volume
159
Grant
EMR/2016/002621/IPC
Fund Ref
Department of Science and Technology, Ministry of Science and Technology, India
Recommended Citation
Kailasa, Suresh Kumar; Koduru, Janardhan Reddy; Baek, Seung Hoon; Wu, Hui Fen; Hussain, Chaudhery Mustansar; and Park, Tae Jung, "Review on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for the rapid screening of microbial species: A promising bioanalytical tool" (2020). Faculty Publications. 4813.
https://digitalcommons.njit.edu/fac_pubs/4813
