Greenness of lab-on-a-chip devices for analytical processes: Advances & future prospects
Document Type
Article
Publication Date
9-20-2022
Abstract
Lab-on-a-chip devices have now-a-days become an important aspect of analytical/bioanalytical chemistry having wide range of applications including clinical diagnosis, drug screening, cell biology, environmental monitoring, food safety analysis etc. Conventional lab-on-a-chip devices generally employ chemicals that are not environmentally friendly and were commonly fabricated on hard plastic platform which are non-degradable and hence ignore the importance of green analytical chemistry. In today's scenario, it is highly imperative to protect our environment by using less toxic and environmentally friendly chemicals/solvents and biocompatible platforms. Accordingly, the present article comprehensively reviews on the various green aspects of lab-on-a-chip devices for analytical processes which aim at fabricating environmentally friendly and cost-effective downsized devices so that the risk factor at the user's end upon longer exposure as well as to the environment can be reduced. The decisive factors for the accomplishment of green aspects of lab-on-a-chip devices including sample preparation using lab-on-a-chip systems to minimize the amount of sample/solvents to few microliters only, substitution of harmful solvents with green alternatives, minimal waste generation or proper treatment of waste and biodegradable and biocompatible platforms for fabricating lab-on-a-chip devices have been discussed in details. Additionally, the challenges that may hinder their commercialization are also critically discussed.
Identifier
85134292514 (Scopus)
Publication Title
Journal of Pharmaceutical and Biomedical Analysis
External Full Text Location
https://doi.org/10.1016/j.jpba.2022.114914
e-ISSN
1873264X
ISSN
07317085
PubMed ID
35843186
Volume
219
Recommended Citation
Agrawal, Arpana; Yıldız, Ümit Yılmaz; Hussain, Chaudhery Ghazanfar; Kailasa, Suresh Kumar; Keçili, Rüstem; and Hussain, Chaudhery Mustansar, "Greenness of lab-on-a-chip devices for analytical processes: Advances & future prospects" (2022). Faculty Publications. 2654.
https://digitalcommons.njit.edu/fac_pubs/2654