Multi-channel recordings of the motor activity from the spinal cord of behaving rats

Document Type

Conference Proceeding

Publication Date

12-1-2006

Abstract

The objective of this study was to extract voluntary motor signals from the rubrospinal tract in behaving rats and study the correlation between these volitional signals and the elbow movements. Multi-contact silicone substrate surface electrodes were implanted chronically at the cervical C5-C6 and C6-C7 levels of the spinal cord. Recordings were made during face cleaning by the animal as this task involves cyclic movements of the forelimbs and does not require any training. Temporal correlation was performed between the recordings of the proximal pair and the distal pair of contacts within a sliding window to determine whether the signals were sensory or motor. Linear regression technique was used to reconstruct the arm movement from the rectified-integrated version of the neural signals. The preliminary data show that motor signals can be successfully recorded from the cervical region of the spinal cord in behaving rats and reconstruction of elbow movements from the neural signals is feasible using these non-penetrating surface electrodes. © 2006 IEEE.

Identifier

34047129321 (Scopus)

ISBN

[1424400325, 9781424400324]

Publication Title

Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings

External Full Text Location

https://doi.org/10.1109/IEMBS.2006.260854

ISSN

05891019

PubMed ID

17946950

First Page

2288

Last Page

2291

Grant

R21HD056963

Fund Ref

Eunice Kennedy Shriver National Institute of Child Health and Human Development

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