A new approach to RNA pseudoknot prediction
Document Type
Conference Proceeding
Publication Date
12-1-2012
Abstract
We present in this paper an ab initio method, named Knot-Fold, for RNA pseudoknot prediction. Our method employs a majority agreement algorithm to predict a set of pseudoknot-free stems using an ensemble of RNA folding tools, and then predicts pseudoknots by utilizing a search technique with a pseudo-probability scoring scheme. Experimental results on PseudoBase data show that Knot-Fold achieves higher sensitivity than related methods. The KnotFold package with documentation is available at http://bioinformatics.njit.edu/ KnotFold.
Identifier
84883638676 (Scopus)
ISBN
[9781618397461]
Publication Title
4th International Conference on Bioinformatics and Computational Biology 2012 Bicob 2012
First Page
151
Last Page
156
Recommended Citation
Spirollari, Junilda; Wang, Jason T.L.; and Wang, Shawn Xiong, "A new approach to RNA pseudoknot prediction" (2012). Faculty Publications. 17969.
https://digitalcommons.njit.edu/fac_pubs/17969
