Dynamics of AIDS manifestation: A mathematical prediction

Document Type

Conference Proceeding

Publication Date

12-1-1990

Abstract

One of the major issues in the study of AIDS is understanding the manifestation and the progression of the disease following HIV transmission. A simulation approach can be used in predicting the various stages from HIV infection to AIDS. A mathematical model of the immune response to HIV is developed here. A set of nonlinear, first-order differential equations is formulated. The model predicts the response of CD4+ cells, cytotoxic and NK cells, polymorphs, and antibodies in the infection. The results of this model are in close agreement with actual clinical observations in patients.

Identifier

0025569214 (Scopus)

ISBN

[0879425598]

Publication Title

Proceedings of the Annual Conference on Engineering in Medicine and Biology

ISSN

05891019

First Page

1196

Last Page

1197

Issue

pt 3

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