Molecular modeling of the histamine H1 receptor

Document Type

Conference Proceeding

Publication Date

1-1-1992

Abstract

The authors review the properties and functional characteristics of the H1 receptor and postulate the nature of the ligand-receptor activation site using molecular modeling techniques. A model of the surface of the active site on the receptor was postulated and constructed using Sybyl software on a personal Iris workstation. The surface properties were inferred using the structure-activity relationships for the competitive antagonists which have been reported in the literature.

Identifier

85065837172 (Scopus)

ISBN

[0780309022]

Publication Title

Proceedings of the IEEE Annual Northeast Bioengineering Conference Nebec

External Full Text Location

https://doi.org/10.1109/NEBC.1992.286001

e-ISSN

21607001

ISSN

1071121X

First Page

156

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