Mathematical modeling of a flat-membrane-controlled release device

Document Type

Article

Publication Date

12-1-1999

Abstract

The closed form solution to a mathematical model of a flat membrane device successfully predicts the release profile of benzoic acid. Physically, the device consists of a given concentration of benzoic acid in octanol (reservoir) bounded by a microporous flat film (Cellgard 2400) with water- filled pores. The prediction shows excellent agreement with the experimentally derived release profile (maximum difference < 10%). Predicted results are obtained from the use of the steady state plus the first term of the transient solution (infinite series) and with the use of the first nonzero eigenvalue.

Identifier

0033504332 (Scopus)

Publication Title

Separation Science and Technology

External Full Text Location

https://doi.org/10.1081/SS-100100770

ISSN

01496395

First Page

2251

Last Page

2258

Issue

11

Volume

34

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