Concise synthesis and enzymatic resolution of L-(+)-homophenylalanine hydrochloride
Document Type
Article
Publication Date
1-1-2002
Abstract
The N-acetyl-homophenylalanine ethyl ester was synthesized by a simple three-step-reaction strategy. L-(+)-homophenylalanine hydrochloride with 98% ee was obtained through a kinetic resolution process using industrial enzyme alcalase. Compared with other methods, this strategy has the advantage of economical and simple procedure giving high product optical purity.
Identifier
0009939368 (Scopus)
Publication Title
Enantiomer
External Full Text Location
https://doi.org/10.1080/10242430210706
ISSN
10242430
PubMed ID
12043941
First Page
1
Last Page
3
Issue
1
Volume
7
Recommended Citation
Zhao, Hua; Luo, Robert G.; Wei, Dean; and Malhotra, Sanjay V., "Concise synthesis and enzymatic resolution of L-(+)-homophenylalanine hydrochloride" (2002). Faculty Publications. 14917.
https://digitalcommons.njit.edu/fac_pubs/14917
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