Computerized cognitive assessment of mild cognitive impairment in urban African Americans

Document Type

Article

Publication Date

1-1-2009

Abstract

Few objective cognitive assessment tools have been validated for mild cognitive impairment (MCI) in African Americans despite higher prevalence of disease. This preliminary study evaluated discriminant validity of a computerized cognitive assessment battery for MCI in an urban African American cohort. Twenty-seven participants with MCI and 22 cognitively healthy individuals completed a multidomain battery (Mindstreams, NeuroTrax Corp, New Jersey). Mild cognitive impairment participants performed more poorly than cognitively healthy participants in all domains, with significant differences in memory (P =.003; d = 0.96), executive function (P =.046; d = 0.64), and overall battery performance (P =.041; d = 0.63). Adjustment for intelligence quotient (IQ) yielded significant differences in memory (P <.001; d = 1.34), executive function (P =.007; d = 0.86), attention (P =.014; d =.80), and overall performance (P =.001; d = 1.09). Such a validated battery may help to address an important clinical need in this population.

Identifier

70349659793 (Scopus)

Publication Title

American Journal of Alzheimer S Disease and Other Dementias

External Full Text Location

https://doi.org/10.1177/1533317509342982

ISSN

15333175

PubMed ID

19700670

First Page

396

Last Page

403

Issue

5

Volume

24

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