Evaluation of foaming of pharmaceutical polymers by CO2 and N2 to enable drug products

Document Type

Conference Proceeding

Publication Date

8-23-2011

Abstract

Gas mediated foaming of extrudate is of interest to the pharmaceutical industry as a method to improve milling performance, to increase surface area for dissolution of molded parts, and to increase the processing window of thermally labile active ingredients via gas-assist extrusion. Pharmaceutical polymers were characterized via rheology and gas solubility measurements for their ability to support a foamed architecture. Finally, batch foaming studies were conducted and the materials characterized for density and cell size.

Identifier

80051821590 (Scopus)

ISBN

[9781617829604]

Publication Title

Annual Technical Conference ANTEC Conference Proceedings

First Page

1224

Last Page

1228

Volume

2

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