A quality-assurance study of ChEBI

Document Type

Conference Proceeding

Publication Date

1-1-2016

Abstract

Ontologies are important components of many health-information systems. The Chemical Entities of Biological Interest (ChEBI) ontology has become a standard reference for chemicals appearing in biological contexts. As such, assuring the quality of its content is imperative. In fact, ChEBI has a dedicated Web page at which errors and inconsistencies in its concepts can be reported. A study of the correctness of a random sample of ChEBI concepts is carried out. The results show that quite a large number of ChEBI concepts suffer from some kind of problematic modeling. For example, we found that 15.5% of the sample concepts exhibited severe errors of commission, including incorrect hierarchical (is a) and lateral relationships. Errors of omission were also prevalent. The overall results of our quality-assurance (QA) study are presented. Suggestions for enhancing the QA processes in place for ChEBI are discussed.

Identifier

85018778756 (Scopus)

Publication Title

Ceur Workshop Proceedings

ISSN

16130073

Volume

1747

Grant

R01CA190779

Fund Ref

National Institutes of Health

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