Document Type
Thesis
Date of Award
9-30-1988
Degree Name
Master of Science in Biomedical Engineering - (M.S.)
Department
Biomedical Engineering Committee
First Advisor
David S. Kristol
Second Advisor
Shlomo Gabbay
Third Advisor
Peter Engler
Abstract
A computerized data acquisition system is presented for the in-vitro determination of the hydrodynamic performance of prosthetic heart valves. High speed data acquisition and ensemble averaging techniques are employed to minimize error and provide a standard for data collection and analysis across a wide range of simulated physiologic conditions. Processing algorithms automatically divide the cardiac cycle into phases based on landmarks in the pressure and flow waveforms, with minimal variability and without operator intervention. The contributions of valve resistance, regurgitation, ejection, leakage, and power loss to hydrodynamic performance are isolated for investigation. Phasic power loss analysis is reviewed as a relative measure of valve merit, with preliminary results revealing a need for further investigation into the clinical significance of such losses.
Recommended Citation
Andrews, John F., "An intelligent computerized pulse-duplicator for the in-vitro evaluation of prosthetic heart valves" (1988). Theses. 3004.
https://digitalcommons.njit.edu/theses/3004
