Date of Award

Spring 2016

Document Type

Thesis

Degree Name

Master of Science in Biomedical Engineering - (M.S.)

Department

Biomedical Engineering

First Advisor

Bryan J. Pfister

Second Advisor

N. Chandra

Third Advisor

Max Roman

Abstract

Deformation of human brain due to acceleration impact has been widely accepted as the direct connection to the Trauma Brain Injury (TBI). However, the limitation of obtaining deformation data of TBI is a major obstacle to understanding TBI mechanism. This experiment mainly focuses on developing a method to measure deformation pattern of brain with blunt injury. First of all, displacement data of markers on sagittal plane of an injury head model was collected using 3D reconstruction software after an impact test. Second, the displacement data was used to calculate 2D Lagrangian strain tensor and the principal strain. The temporal and spatial results of principal strain under different variables including impact velocity (5 mile/hour, 3 mile/ hour), impact location (crown head, front head) and concentration of gel used to build the brain model (10%, 20%) were compared. The results shown larger strain values within the variables of higher impact velocity, crown head impact location and 10% gel. The spatial location results shown clearly the difference in terms of deformation pattern of different impact locations.

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