Document Type

Thesis

Date of Award

10-31-1993

Degree Name

Master of Science in Biomedical Engineering - (M.S.)

Department

Biomedical Engineering Committee

First Advisor

H. Michael Lacker

Second Advisor

Swamy Laxminarayan

Third Advisor

David S. Kristol

Abstract

Our present study is to find out how the short and long nephrons are interacting in the human kidney to adjust the flow in the collecting duct to have the maximum flow during the diluting mode and minimum flow during the concentrating mode. The best lengths for the short nephron and long nephron are calculated during the concentrating mode and the diluting mode by using the Newton-Raphson method. If one wants the kidney to perform only the above mentioned functions, a design criteria for an artificial kidney has been proposed. These studies have provided qualitative information regarding the concentrating mechanism and illustrates well the problem involved in attempting to describe accurately the function of an organ like kidney.

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