Date of Award

1-31-1993

Document Type

Thesis

Degree Name

Master of Science in Biomedical Engineering - (M.S.)

Department

Biomedical Engineering Committee

First Advisor

Engler, Peter

Second Advisor

Kristol, David S.

Third Advisor

Spillert, Charles R.

Abstract

In this paper we present a new method to analyze whole blood coagula¬tion dynamics. Using a PC-286 computer equipped with a DASH-16 AID board.

The row data from a SONOCLOT analyzer is amplified and digitized on the DASH-16 A/D board and stored in the PC-286 hard disk. The data is fil¬tered through a digital Butterworth filter. The filtered data is then fit to math¬ematical relationship by the least square method. The coefficients which define the mathematical relationships are used to identify blood specimens with normal coagulation dynamics as distinguished from specimens with abnormal dynamics.

The digital filter and curve-fitting routine are implemented on MATLAB software.

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