Membrane systems for pharmaceutical applications

Document Type

Syllabus

Publication Date

4-13-2019

Abstract

There have been limited applications of membrane technologies in the pharmaceutical industry during active pharmaceutical ingredient (API) processing in the presence of organic solvents. The membrane technologies that are being used and/or explored in a more than cursory fashion in pharmaceutical processing are pervaporation and organic solvent nanofiltration. The majority of potential pervaporation applications in the pharmaceutical industry are related to dehydration of pharmaceutical streams. This chapter examines in more detail the work that has been performed up to now in the dehydration of organic solvents with ceramic membranes for two reasons. First, ceramic membranes are considered the most appropriate for applications in the pharmaceutical industry. Second, the work performed in pure solvents can serve as a basis for the design of applications with streams containing an API. The chapter also briefly focuses on membrane solvent extraction.

Identifier

85103345072 (Scopus)

ISBN

[9781119285496, 9781119600800]

Publication Title

Chemical Engineering in the Pharmaceutical Industry

External Full Text Location

https://doi.org/10.1002/9781119600800.ch32

First Page

733

Last Page

750

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