A Comparative Review of Key Isothiocyanates and Their Health Benefits

Document Type

Article

Publication Date

3-1-2024

Abstract

Isothiocyanates are biologically active products resulting from the hydrolysis of glucosinolates predominantly present in cruciferous vegetables belonging to the Brassicaceae family. Numerous studies have demonstrated the diverse bioactivities of various isothiocyanates, encompassing anticarcinogenic, anti-inflammatory, and antioxidative properties. Nature harbors distinct isothiocyanate precursors, glucosinolates such as glucoraphanin and gluconastrin, each characterized by unique structures, physical properties, and pharmacological potentials. This comprehensive review aims to consolidate the current understanding of Moringa isothiocyanates, mainly 4-[(α-L-rhamnosyloxy) benzyl] isothiocyanate), comparing this compound with other well-studied isothiocyanates such as sulforaphane and phenyl ethyl isothiocyanates. The focus is directed toward elucidating differences and similarities in the efficacy of these compounds as agents with anticancer, anti-inflammatory, and antioxidative properties.

Identifier

85188952772 (Scopus)

Publication Title

Nutrients

External Full Text Location

https://doi.org/10.3390/nu16060757

e-ISSN

20726643

PubMed ID

38542669

Issue

6

Volume

16

Grant

2023-67017-39267

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