Building a model of the brain: from detailed connectivity maps to network organization

Document Type

Article

Publication Date

10-1-2021

Abstract

The field of computational modeling of the brain is advancing so rapidly that now it is possible to model large scale networks representing different brain regions with a high level of biological detail in terms of numbers of neurons and synapses. For a theoretician approaching a neurobiological question, it is important to analyze the pros and cons of each of the models available. Here, we provide a tutorial review on recent models for different brain circuits, which are based on experimentally obtained connectivity maps. We discuss particularities that may be relevant to the modeler when choosing one of the reviewed models. The objective of this review is to give the reader a fair notion of the computational models covered, with emphasis on the corresponding connectivity maps, and how to use them.

Identifier

85107817296 (Scopus)

Publication Title

European Physical Journal Special Topics

External Full Text Location

https://doi.org/10.1140/epjs/s11734-021-00152-7

e-ISSN

19516401

ISSN

19516355

First Page

2887

Last Page

2909

Issue

14-15

Volume

230

Grant

2013/07699-0

Fund Ref

Fundação de Amparo à Pesquisa do Estado de São Paulo

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