Bursting in 2-compartment neurons: A case study of the Pinsky-Rinzel model
Document Type
Syllabus
Publication Date
1-1-2005
Abstract
The two-compartment Pinsky-Rinzel model of a hippocampal CA3 pyramidal neuron consists of electrically coupled soma and dendritic compartments, each with active ionic conductances. This model has been widely used in a variety of contexts, but little analysis has been performedon its bursting solutions. In this chapter, we provide a geometric framework to study the Pinsky-Rinzel model. Using a combination of analysis and simulations, we identify neuronal mechanisms responsible for certain salient features of the model such as burst initiation and somatic-dendritic ping-pong. Some of these mechanisms are then demonstrated in a conceptually simpler, two-compartment Morris-Lecar model.
Identifier
60449115328 (Scopus)
ISBN
[981256506X, 9789812565068, 9789812703231]
Publication Title
Bursting the Genesis of Rhythm in the Nervous System
External Full Text Location
https://doi.org/10.1142/9789812703231_0005
First Page
123
Last Page
144
Recommended Citation
Bose, Amitabha and Booth, Victoria, "Bursting in 2-compartment neurons: A case study of the Pinsky-Rinzel model" (2005). Faculty Publications. 19898.
https://digitalcommons.njit.edu/fac_pubs/19898
