Monte Carlo simulation of light-tissue interaction: Three-dimensional simulation for trans-illumination-based imaging of skin lesions
Document Type
Article
Publication Date
7-1-2005
Abstract
Three-dimensional, voxel-based, and wavelength-dependent skin lesion models are developed and simulated using Monte Carlo techniques. The optical geometry of the Nevoscope with trans-illumination is used in the simulations for characterizing the lesion thickness. Based on the correlation analysis between the lesion thickness and the diffuse reflectance, optical wavelengths are selected for multispectral imaging of skin lesions using the Nevoscope. Tissue optical properties reported by various researchers are compiled together to form a voxel library. Tissue models used in the simulations are developed using the voxel library which offers flexibility in updating the optical properties and adding new media types into the models independent of the Monte Carlo simulation code. © 2005 IEEE.
Identifier
21844465713 (Scopus)
Publication Title
IEEE Transactions on Biomedical Engineering
External Full Text Location
https://doi.org/10.1109/TBME.2005.847546
ISSN
00189294
PubMed ID
16041986
First Page
1227
Last Page
1236
Issue
7
Volume
52
Grant
RG-99-0127
Fund Ref
Whitaker Foundation
Recommended Citation
Patwardhan, Sachin V.; Dhawan, Atam P.; and Relue, Patricia A., "Monte Carlo simulation of light-tissue interaction: Three-dimensional simulation for trans-illumination-based imaging of skin lesions" (2005). Faculty Publications. 19651.
https://digitalcommons.njit.edu/fac_pubs/19651
