Increased paraoxon detection by acetylcholinesterase inactivation with ionic liquid additives

Authors

Chengdong Zhang, New Jersey Institute of Technology
Sanjay V. Malhotra, New Jersey Institute of Technology

Document Type

Article

Publication Date

9-15-2005

Abstract

This is the first study using ionic liquids (ILs) as additive in the aqueous solvent medium for detection of paraoxon by acetylcholinesterase inhibition method. A systematic comparison of various ILs with organic solvents has been made. The aqueous buffer solution containing ionic liquid ethylpyridinium hexafluorophosphate [EtPy]⁺[PF6] ^- has been found to give the best results. The inhibition kinetic follows the first order model. Ionic liquids modified aqueous solutions show the potential to provide a promising and effective medium in detection of paraoxon with acetylcholinesterase. © 2005 Elsevier B.V. All rights reserved.

Identifier

24144440439 (Scopus)

Publication Title

Talanta

External Full Text Location

https://doi.org/10.1016/j.talanta.2005.03.037

ISSN

00399140

First Page

560

Last Page

563

Issue

3

Volume

67

Recommended Citation

Zhang, Chengdong and Malhotra, Sanjay V., "Increased paraoxon detection by acetylcholinesterase inactivation with ionic liquid additives" (2005). Faculty Publications. 19562.
https://digitalcommons.njit.edu/fac_pubs/19562