Review of data analysis methodologies in the study of ionic channel dynamics

Document Type

Conference Proceeding

Publication Date

12-1-1991

Abstract

Fluctuation and ensemble analysis techniques are investigated to understand the single-channel dynamics of calcium channels of hippocampal neurons. Classical voltage-clamp techniques are used to record the whole-cell calcium currents in hippocampal neurons which were dissociated from adult mice. Fluctuation analysis results indicate two frequencies (two open times), in contrast to the results obtained by classical techniques which indicated single frequency (single open time). The unitary current values obtained by classical techniques are slightly higher than the values obtained by using the ensemble analysis procedure.

Identifier

0026268057 (Scopus)

ISBN

[0780302168]

Publication Title

Proceedings of the Annual Conference on Engineering in Medicine and Biology

ISSN

05891019

First Page

1531

Last Page

1532

Issue

pt 4

Volume

13

This document is currently not available here.

Share

COinS