Fatigue in multiple sclerosis using heart rate variability

Document Type

Conference Proceeding

Publication Date

12-1-1991

Abstract

A study was made of physiological responses to treadmill exercise, and it was found that MS (multiple sclerosis) subjects displayed abnormalities of vagal tone. Persons with MS began exercise with much lower vagal tone than normal controls, reached a point at which there was complete loss of vagal tone earlier, and stopped exercising at a lower work load than age and sex matched normal controls. The data provide new evidence that points to a nervous system defect that contributes to fatigue and activity limitation in MS. The loss of energy conserving mechanisms related to impaired vagal function appears to accelerate energy expenditure during exercise and might contribute to fatigue at rest.

Identifier

0026406412 (Scopus)

ISBN

[0780302168]

Publication Title

Proceedings of the Annual Conference on Engineering in Medicine and Biology

ISSN

05891019

First Page

664

Last Page

665

Issue

pt 2

Volume

13

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