Regulating firing rate of networks of pyramidal cells

Document Type

Article

Publication Date

6-1-2001

Abstract

In a minimal network model consisting of two pyramidal cells and one interneuron, we show how excitation and inhibition cooperate to produce firing rate changes in pyramidal cells that are consistent with observed place cell firing in region CA3 of the hippocampus. We show that inhibition from a common interneuron can synchronize networks of pyramidal cells with no direct connections. Moreover, recurrent excitation together with common inhibition can modulate burst profiles of synchronously firing cells from complex bursts to bursts with multiple spike to single spikes. © 2001 Elsevier Science B.V. All rights reserved.

Identifier

18844481162 (Scopus)

Publication Title

Neurocomputing

External Full Text Location

https://doi.org/10.1016/S0925-2312(01)00380-0

ISSN

09252312

First Page

497

Last Page

504

Volume

38-40

Grant

-9722946 VB

Fund Ref

National Science Foundation

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