Computer-aided differential diagnosis of breast cancer and fibroadenomatosis based on malignancy associated changes in buccal epithelium

Document Type

Article

Publication Date

12-1-2001

Abstract

A computer method for the diagnosis of breast cancer (CMG) and fibroadenometosis (FAM) is developed. Based on a single analysis of patient's buccal scrapes, the probability of error in the diagnosis of CMG and the probability of non-acceptance of decision do not exceed 6%. For patients suffering from FAM the probability of error in the diagnosis is practically zero, and the probability of non-acceptance of decision is 43%. If the decision is not accepted, repeated analysis is performed taking more trials (buccal scrapes). If the analysis results are similar after n independent trials, then the probability of non-acceptance of decision is approximately (1/2)n. The computer method of diagnosis is supplementary to, and should be used only in conjunction with, other methods of clinical examination such as mammography, ultrasound examination, etc. The method can be applied to the mass screening of patients for early detection of breast cancer, and to the selection of patients who are in a high risk category.

Identifier

0035690450 (Scopus)

Publication Title

Automedica

ISSN

00950963

First Page

135

Last Page

164

Issue

3-4

Volume

19

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