Enzymatic resolution of amino acid esters using ionic liquid N-ethyl pyridinium trifluoroacetate

Authors

Hua Zhao, New Jersey Institute of Technology
Sanjay V. Malhotra, New Jersey Institute of Technology

Document Type

Article

Publication Date

1-1-2002

Abstract

A new ionic liquid, N-ethyl pyridinium trifluoroacetate, was used with a commercial protease to resolve N-acetyl amino acid esters in place of traditional organic solvents. Products with enantiomeric excess (ee) between 86-97% were obtained. These results show that with low concentration of this new ionic liquid, the enzymatic resolution can be increased considerably depending upon the substrate being used.

Identifier

0036338863 (Scopus)

Publication Title

Biotechnology Letters

External Full Text Location

https://doi.org/10.1023/A:1016205924504

ISSN

01415492

First Page

1257

Last Page

1259

Issue

15

Volume

24

Recommended Citation

Zhao, Hua and Malhotra, Sanjay V., "Enzymatic resolution of amino acid esters using ionic liquid N-ethyl pyridinium trifluoroacetate" (2002). Faculty Publications. 14781.
https://digitalcommons.njit.edu/fac_pubs/14781