Extraction and modeling of the Oscillatory Potential: Signal conditioning to obtain minimally corrupted Oscillatory Potentials

Document Type

Article

Publication Date

3-27-2002

Abstract

A method of extracting a temporally bounded component of a composite signal has been developed which minimizes data corruption in signal processing. The composite signal is windowed in the time domain, padding signals are attached, and finally, the conditioned signal is filtered to extract the component of interest. The method has been utilized to extract the Oscillatory Potential (OP) from the Electroretinogram (ERG). ERGs can contain impulse like transients, including flash artifacts and a-b wave transition, which may not be related to the Oscillatory Potential. Such transients will stimulate a filter, yielding its natural (filter) response and thus distort the actual OP signal. To avoid this effect, time-domain windowing and signal conditioning is used to extract the OP from the ERG. The extraction and modeling approach is applied to ERGs obtained from patients with recent monocular central retinal vein occlusion (CRVO). Model parameters clearly differentiate affected from fellow eyes and show subtle differences between eyes with benign and complicated outcomes.

Identifier

0036124683 (Scopus)

Publication Title

Documenta Ophthalmologica

External Full Text Location

https://doi.org/10.1023/A:1014474026114

ISSN

00124486

PubMed ID

11949807

First Page

37

Last Page

55

Issue

1

Volume

104

Grant

R03EY010590

Fund Ref

National Eye Institute

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