The critical mediating roles of the middle temporal gyrus and ventrolateral prefrontal cortex in the dynamic processing of interpersonal emotion regulation
Document Type
Article
Publication Date
10-15-2024
Abstract
Interpersonal emotion regulation (IER) is a crucial ability for effectively recovering from negative emotions through social interaction. It has been emphasized that the empathy network, cognitive control network, and affective generation network sustain the deployment of IER. However, the temporal dynamics of functional connectivity among these networks of IER remains unclear. This study utilized IER task-fMRI and sliding window approach to examine both the stationary and dynamic functional connectivity (dFC) of IER. Fifty-five healthy participants were recruited for the present study. Through clustering analysis, four distinct brain states were identified in dFC. State 1 demonstrated situation modification stage of IER, with strong connectivity between affective generation and visual networks. State 2 exhibited pronounced connectivity between empathy network and both cognitive control and affective generation networks, reflecting the empathy stage of IER. Next, a ‘top-down’ pattern is observed between the connectivity of cognitive control and affective generation networks during the cognitive control stage of state 3. The affective response modulation stage of state 4 mainly involved connections between empathy and affective generation networks. Specifically, the degree centrality of the left middle temporal gyrus (MTG) mediated the association between one's IER tendency and the regulatory effects in state 2. The betweenness centrality of the left ventrolateral prefrontal cortex (VLPFC) mediated the association between one's IER efficiency and the regulatory effects in state 3. Altogether, these findings revealed that dynamic connectivity transitions among empathy, cognitive control, and affective generation networks, with the left VLPFC and MTG playing dominant roles, evident across the IER processing.
Identifier
85204405501 (Scopus)
Publication Title
NeuroImage
External Full Text Location
https://doi.org/10.1016/j.neuroimage.2024.120789
e-ISSN
10959572
ISSN
10538119
PubMed ID
39159702
Volume
300
Grant
NSFC82250410380
Fund Ref
National Natural Science Foundation of China
Recommended Citation
Wang, Jiazheng; Yang, Zhenzhen; Klugah-Brown, Benjamin; Zhang, Tao; Yang, Jiemin; Yuan, Jia Jin; and Biswal, Bharat B., "The critical mediating roles of the middle temporal gyrus and ventrolateral prefrontal cortex in the dynamic processing of interpersonal emotion regulation" (2024). Faculty Publications. 137.
https://digitalcommons.njit.edu/fac_pubs/137
