EProbalign: Generation and manipulation of multiple sequence alignments using partition function posterior probabilities
Document Type
Article
Publication Date
7-1-2007
Abstract
Probalign computes maximal expected accuracy multiple sequence alignments from partition function posterior probabilities. To date, Probalign is among the very best scoring methods on the BAliBASE, HOMSTRAD and OXBENCH benchmarks. Here, we introduce eProbalign, which is an online implementation of the approach. Moreover, the eProbalign web server doubles as an online platform for post-alignment analysis. The heartand-soul of the post-alignment functionality is the Probalign Alignment Viewer applet, which provides users a convenient means to manipulate the alignments by posterior probabilities. The viewer can also be used to produce graphical and text versions of the output. The eProbalign web server and underlying Probalign source code is freely accessible at http://probalign.njit.edu. © 2007 The Author(s).
Identifier
34547567393 (Scopus)
Publication Title
Nucleic Acids Research
External Full Text Location
https://doi.org/10.1093/nar/gkm267
e-ISSN
13624962
ISSN
03051048
PubMed ID
17485479
First Page
W675
Last Page
W677
Issue
SUPPL.2
Volume
35
Grant
R01GM073082
Fund Ref
National Institutes of Health
Recommended Citation
Chikkagoudar, Satish; Roshan, Usman; and Livesay, Dennis, "EProbalign: Generation and manipulation of multiple sequence alignments using partition function posterior probabilities" (2007). Faculty Publications. 13403.
https://digitalcommons.njit.edu/fac_pubs/13403
