Synthesis and structural characterization of block and random low molecular weight copolymers composed of l-lactic acid and isosorbide succinate moieties

Authors

Romeu Casarano, Universidade de São Paulo
Denise F.S. Petri, Universidade de São Paulo
Michael Jaffe, New Jersey Institute of Technology
Luiz H. Catalani, Universidade de São Paulo

Document Type

Article

Publication Date

1-1-2009

Abstract

Isosorbide succinate moieties were incorporated into poly(L-lactide) (PLLA) backbone in order to obtain a new class of biodegradable polymer with enhanced properties. This paper describes the synthesis and characterization of four types of low molecular weight copolymers. Copolymer I was obtained from monomer mixtures of L-lactide, isosorbide, and succinic anhydride; II from oligo(L-lactide) (PLLA), isosorbide, and succinic anhydride; III from oligo(isosorbide succinate) (PIS) and L-lactide; and IV from transesterification reactions between PLLA and PIS. MALDI-TOFMS and ¹³C-NMR analyses gave evidence that co-oligomerization was successfully attained in all cases. The data suggested that the product I is a random co-oligomer and the products II-IV are block co-oligomers. © 2009 Sociedade Brasileira de Química.

Identifier

70549097166 (Scopus)

Publication Title

Journal of the Brazilian Chemical Society

External Full Text Location

https://doi.org/10.1590/S0103-50532009000800005

e-ISSN

16784790

ISSN

01035053

First Page

1414

Last Page

1424

Issue

8

Volume

20

Recommended Citation

Casarano, Romeu; Petri, Denise F.S.; Jaffe, Michael; and Catalani, Luiz H., "Synthesis and structural characterization of block and random low molecular weight copolymers composed of l-lactic acid and isosorbide succinate moieties" (2009). Faculty Publications. 12259.
https://digitalcommons.njit.edu/fac_pubs/12259