Consensus structure prediction for RNA alignments

Document Type

Syllabus

Publication Date

1-1-2009

Abstract

RNA secondary structure prediction has been studied for quite awhile. Many minimum free energy (MFE) methods have been developed for predicting the secondary structures of single RNA sequences, such as mfold [1], RNAfold [2], MPGAfold [3], as well as recent tools presented in the literature [4, 5]. However, the accuracy of predicted structures is far from perfect. As evaluated by Gardner and Giegerich [6], the accuracy of the MFE methods for single sequences is 73% when averaged over many different RNAs.

Identifier

85056374572 (Scopus)

ISBN

[9781420086843, 9781420086850]

Publication Title

Biological Data Mining

First Page

1

Last Page

26

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