The Biology of Bone and Ligament Healing

Authors

Jessica A. Cottrell, Seton Hall University
Jessica Cardenas Turner, Newark College of Engineering
Treena Livingston Arinzeh, Newark College of Engineering
J. Patrick O'Connor, Rutgers New Jersey Medical School

Document Type

Article

Publication Date

12-1-2016

Abstract

This review describes the normal healing process for bone, ligaments, and tendons, including primary and secondary healing as well as bone-to-bone fusion. It depicts the important mediators and cell types involved in the inflammatory, reparative, and remodeling stages of each healing process. It also describes the main challenges for clinicians when trying to repair bone, ligaments, and tendons with a specific emphasis on Charcot neuropathy, fifth metatarsal fractures, arthrodesis, and tendon sheath and adhesions. Current treatment options and research areas are also reviewed.

Identifier

84996503818 (Scopus)

Publication Title

Foot and Ankle Clinics

External Full Text Location

https://doi.org/10.1016/j.fcl.2016.07.017

e-ISSN

15581934

ISSN

10837515

PubMed ID

27871408

First Page

739

Last Page

761

Issue

4

Volume

21

Grant

CSCR16ERG014

Fund Ref

New Jersey Commission on Spinal Cord Research

Recommended Citation

Cottrell, Jessica A.; Turner, Jessica Cardenas; Arinzeh, Treena Livingston; and O'Connor, J. Patrick, "The Biology of Bone and Ligament Healing" (2016). Faculty Publications. 10129.
https://digitalcommons.njit.edu/fac_pubs/10129